Objective: To study the preparation of pilocarpine nitrate eye-drops, chitosan was used adhesive to increase the effect and decrease the dosage. 前言:目的:以壳聚糖为增黏剂,制备硝酸毛果芸香碱壳聚糖滴眼液,以增强其疗效,减少给药次数。
Preparation and in Vitro Release of Ophthalmic in-situ Gels of Pilocarpine Nitrate 硝酸毛果芸香碱原位凝胶滴眼剂的制备及体外释放度评价
Objective: To observe and study the effects of pilocarpine nitrate injection on the pupil contraction, irritation and toxic reaction in experimental rabbits. 目的:观察硝酸毛果芸香碱注射液对实验性家兔眼睛缩瞳作用及刺激性和毒性反应。
Conclusion: 1% Pilocarpine Nitrate will be an ideal solution that can be used in the pupil contraction operation. And toxic side effects is less than 2% obviously. 结论:1%硝酸毛果芸香碱注射液的缩瞳作用可达到临床要求,而且毒副作用明显小于2%硝酸毛果芸香碱注射液。
A Controlled Clinical Study of Pilocarpine Nitrate in the Treatment of Dry Mouth Caused by Psychotropic Drugs 毛果芸香碱治疗精神药物所致口干的临床对照研究